Evolutionary Study of Protein Short Tandem Repeats in Protein Families

Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution these can be assessed by using groups homologous sequences, which help pointing events unit duplication or deletion. High pressure a protein family for variation given type repeat might point their function. Here, we propose the analysis families calculate short tandem (pSTRs) sequence and assess variability within terms number units. To facilitate this analysis, developed pSTR tool, method analyze pairwise comparisons between evolutionarily related sequences. We evaluated 12 complete metazoan proteomes. hypothesize that with more dynamic ensembles could reflect particular roles processes require adaptability.